Fulminant hepatitis subsequent to reactivation of precore mutant hepatitis B virus in a patient with lymphoma treated with chemotherapy and rituximab.
نویسندگان
چکیده
We report a case of a precore mutant hepatitis B virus (HBV) reactivation in a patient with follicular lymphoma who was treated simultaneously with chemotherapy (cyclophosphamide, vincristine and prednisone) and rituximab, occurred five months after the end of therapy. Despite lamivudine therapy, she died because of fulminant hepatitis. This case illustrates the possibility of late reactivations of HBV after immunosuppressive or cytotoxic therapies, including rituximab. In these patients, prophylaxis with lamivudine seems justified. Haematologica 2007; 88:(7)e94-e95
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ورودعنوان ژورنال:
- Haematologica
دوره 88 6 شماره
صفحات -
تاریخ انتشار 2003